APPLICATION OF A NEW NONINVASIVE DIAGNOSTIC METHOD OF MAIN ARTERIES WITH THE HELP OF ECHOTRACKING TECHNOLOGY IN PATIENTS WITH CORONARY HEART DISEASE

Oleynikov Valentin Elivich, Doctor of medical sciences, professor, head of sub-department of therapeutics, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), oleynikoff@sura.ru
Salyamova Lyudmila Ivanovna, Candidate of medical sciences, associate professor, sub-department of therapeutics, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), l.salyamova@yandex.ru
Mel'nikova Evgeniya Aleksandrovna, Assistant, sub-department of therapeutics, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), melnikova1910@gmail.com
Tomashevskaya Yuliya Anatol'evna, Candidate of medical sciences, associate professor, sub-department of therapeutics, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), t.julia74@mail.ru
Khromova Angelina Anatol'evna, Assistant, sub-department of therapeutics, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), hromova-a.a@yandex.ru

616.133

10.21685/2072-3032-2016-2-5

Backgrounds. The object of the work is to examine parameters of local vascular rigidity based on the data obtained by a new noninvasive echotracking technology in patients with coronary heart disease.
Materials and Methods. We examined 78 patients with coronary heart disease aged 40 to 69 years old. The patients were examined by the ultrasound invastigation of common carotid arteries using the My LAB 90 device (product of “Esaote”, Italy) with echotracking technology. To determine the age standard, the patients were divided into three groups: 40–49, 50–59 and 60–69 years old. To study the influence of high blood pressure on the degree of violations of structural and functional properties of the vascular wall, all patients with coronary heart disease were divided into two groups: patients with normal blood pressure and patients with hypertension.
Results. Patients with coronary heart disease in various age groups have a pro-gressive increase of width on the intima-media complex QIMT. The local pressure in the common carotid artery (loc Psys, loc Pdia, P(T1)) prevailed in patients with cor-onary heart disease of the older age group in comparison to patients under 50 years old. Patients under 50 had a negative value of the augmentation index (Aix), patients of 50–59 had a positive value, and the maximum was revealed in patients over 60. According to the comparative analysis of normotensive patients with coro-nary heart disease and hypertension, we can see an increase of systolic pressure loc Psys, pressure in local point P(T1), β and α regidity index, local race of pulse wave PWV in the second group. At the same time we see a decrease of the coefficient of transverse compliance CC and stretchability DC.
Conclusion. With the age, the progression of arteriosclerosis in carotid arteries revealed in patients with coronary heart disease has been revealed. The increase of local pressure is followed by the decrease of the damping function. This indicates the increase of the augmentation index in the examined age groups. The presence of hypertension in patients with coronary heart disease is involved with the critical deteriorating of most of the indicators characterizing structural and functional properties of carotid arteries.

echotracking, local vascular rigidity, coronary heart disease, arterial hypertension.

1. Roger V., Go A., Lloyd-Jones D. et al. Circulation. 2012, vol. 125, pp. 2–220.
2. Grundy S., Kleeman J., Merz C. et al. Circulation. 2004, vol. 110, pp. 227–239.
3. Natsional'nye klinicheskie rekomendatsii (tretiy peresmotr) [National clinical guidelines (third revision)]. Moscow: Silitseya-Poligraf, 2008, p. 512.
4. Hoeks A. P., Brands P. J., Smeets F. A. et al. Ultrasound Med. Biol. 1990, no. 16 (2), pp. 121–128.
5. Tripoten' M. I., Balakhonova T. V., Rogoza A. N. Ul'trazvukovaya i funktsional'naya diagnostika [Ultrasound and functional diagnostics]. 2011, no. 6, pp. 50–56.
6. Touboul P.-J., Hennerici M. G., Meairs S. et al. Cerebrovasc Dis. 2007, vol. 23, pp. 75–80.
7. Benetos A., Waeber B., Izzo J., Mitchell G. et al. Am J Hypertens. 2002, no. 15 (12), pp. 1101-8.
8. Sehestedt T., Jeppersen J., Hansen T. W. et al. Eur Heart J. 2010, vol. 31, pp. 883–891.
9. Yang E. Y., Chambless L., Sharrett A. R. et al. Stroke. 2012, no. 43 (1), pp. 103–108.
10. Laurent S., Cockcroft J., Van Bortel L., et al. Eur Heart J. 2006, no. 27 (21), pp. 2588–2605.